Erytromicin

Drug name: Erytromicin

Other names used:

• Abboticin®
• Abboticin-ES®
• E-Base®
• E-Mycin®
• E.E.S. Granules®
• E.E.S.-200®
• E.E.S.-400®
• E.E.S.-400 Filmtab®
• Ery-Tab®
• Eryc®
• Erycin and PCE Dispertab.®
• Erymax®
• Erypar®
• EryPed®
• Eryped 200®
• Eryped 400®
• Erythrocin Stearate Filmtab®
• Erythrocot®
• Erythroped®
• Ilosone®
• MY-E®
• Pediamycin®
• Robimycin®
• Zineryt®

Active Ingredients: Erythromycin

Therapeutic actions: Erythromycin is a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin.

Indications: Erythromycin is often used for people who have an allergy to penicillins. For respiratory tract infections, it has better coverage of atypical organisms, including mycoplasma and Legionellosis. It is also used to treat outbreaks of chlamydia, syphilis, acne and gonorrhea.

Contraindications and cautions: Erythromycin is contraindicated in patients with known hypersensitivity to this antibiotic. Erythromycin is contraindicated in patients taking terfenadine, astemizole, or cisapride.

Adverse effects: Erythromycin inhibits the cytochrome P450 system, which can cause it to affect the metabolism of many different drugs.
Gastrointestinal disturbances such as diarrhea, nausea, abdominal pain and vomiting are fairly common so it tends not to be prescribed as a first-line drug. However, erythromycin may be useful in treating gastroparesis due to this pro-motility effect. Intravenous erythromycin may also be used in endoscopy as an adjunct to clear gastric contents.
More serious side-effects, such as arrhythmia, reversible deafness are rare. allergic reactions, while uncommon, may occur, ranging from urticaria to anaphylaxis. Cholestasis, Stevens-Johnson syndrome and toxic epidermal necrolysis are some other rare side effects that may occur.
Erythromycin has been shown to increase the probability of pyloric stenosis in children whose mothers took the drug during the late stages of pregnancy or while nursing.

Interactions: Erythromycin use in patients who are receiving high doses of theophylline may be associated with an increase in serum theophylline levels and potential theophylline toxicity. In case of theophylline toxicity and/or elevated serum theophylline levels, the dose of theophylline should be reduced while the patient is receiving concomitant erythromycin therapy.
Concomitant administration of erythromycin and digoxin has been reported to result in elevated digoxin serum levels.
There have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants were used concomitantly. Increased anticoagulation effects due to interactions of erythromycin with various oral anticoagulents may be more pronounced in the elderly. Concurrent use of erythromycin and ergotamine or dihydroergotamine has been associated in some patients with acute ergot toxicity characterized by severe peripheral vasospasm and dysesthesia.
Erythromycin has been reported to decrease the clearance of triazolam and midazolam and thus may increase the pharmacologic effect of these benzodiazepines.

Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.