Klabax
Drug name: Klabax
Other names used:
- Claridar®
- Claripen®
Active Ingredients:
- clarithromycin
Therapeutic actions: Clarithromycin prevents bacteria from growing, by interfering with their protein synthesis. Clarithromycin binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Clarithromycin has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila. Besides this bacteriostatic effect, clarithromycin also has bactericidal effect on certain strains such as Haemophilus influenzae, Streptococcus and Neisseria gonorrhoeae.
Indications: Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydia pneumoniae or TWAR), skin and skin structure infections, and, in and AIDS patients to prevent, and to treat, disseminated Mycobacterium avium complex (MAC). In addition, it is sometimes used to treat Legionellosis.
Contraindications and cautions: Clarithromycin should be used with caution if the patient has liver or kidney disease, certain heart problems (e.g., QT prolongation or bradycardia), or an electrolyte imbalance (e.g., low potassium or magnesium levels). Many other can interact with clarithromycin, which is why the doctor should be informed of any other the patient is taking concomitantly. Clarithromycin is almost never used in HIV patients due to significant interaction with HIV drugs.
reactions can occur with clarithromycin use. People with a history of allergy, asthma, hay fever or hives seem to be more susceptible to these reactions. The reaction can be immediate and severe.
Allergic include wheezing, hives, itching, swelling, spasms in the throat and breathing tubes, swelling of the face and neck, joint and muscle pain, difficulty breathing, fever and skin rashes. Rashes can range in severity, the most serious cases being toxic epidermal necrolysis and Stevens-Johnson syndrome. Nausea and vomiting are not symptoms of an allergic reaction.
Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this will experience that or any side effect.
Most common side-effects are gastrointestinal: diarrhea, nausea, abdominal pain and vomiting. Less common side-effects include headaches, rashes, alteration in senses of smell and taste, including a metallic taste that lasts the entire time one takes it. Dry mouth, anxiety, hallucinations, and nightmares have also been reported. In more serious cases it has been known to cause jaundice, other liver disorders, and kidney problems including kidney failure. Inform your doctor immediately if side effects are extremely bothersome or serious. Clarithromycin may cause false positives on urine screens for cocaine.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
Interactions: Tell your doctor or pharmacist what you are already taking, including those bought without a prescription and medicines, before you start treatment with this medicine.
Interactions with clarithromycin may occur with the following:
- astemizole (Hismanal)
- blood thinners (Coumadin)
- carbamazepine (Tegretol)
- cisapride (Propulsid)
- cyclosporine (Sandimmune, Neoral)
- digoxin (Lanoxin)
- disopyramide (Norpace)
- ergotamine (Cafergot)
- fluconazole (Diflucan)
- lovastatin (Mevacor)
- phenytoin (Dilantin)
- theophylline (Theo-Dur)
- triazolam (Halcion)
- valproate (Depakene)
- zidovudine (Retrovir)
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
