Siprobel

Drug name: Siprobel

Other names used:

• CIPROLEB®

Active Ingredients:

• Ciprofloxacin

Therapeutic actions: Siprobel contains the active ingredient Ciprofloxacin. Ciprofloxacin is a fluoroquinolones antibiotic. Ciprofloxacin works by inhibiting the enzyme called DNA-gyrase. DNA-gyrase is essential ferment for DNA(genetic material) replication and protein synthesis. Inhibiting the enzyme makes bacteria nonviable and bacteria die. Ciprofloxacin is a broad spectrum antibiotic that is effective against gram-positive and gram-negative bacteria. Ciprofloxacin acts both on proliferous bacteria and microorganisms being in the resting phase.

Indications: Siprobel is used to treat infectious diseases caused by susceptible to ciprofloxacin microorganisms:

• Urinary tract infections
• Acute uncomplicated cystitis in females
• Chronic bacterial prostatitis
• Lower respiratory tract infections (including acute exacerbations of chronic bronchitis)
• Acute sinusitis
• Skin and skin structure infections
• Bone and joint infections
• Complicated intra-abdominal infections (in combination with metronidazole)
• Infectious diarrhea;
• Typhoid fever due to typhi (eradication of chronic typhoid carrier state has not been proven)
• Uncomplicated cervical and urethra (due to N. gonorrhoeae )
• Pneumonia
• empirical therapy for febrile neutropenic patients

Contraindications and cautions: You should not use Siprobel if any of the following conditions apply to you:

• Known hypersensitivity or to Ciprofloxaxin or other fluoroquinolones.
• Pregnancy
• Breastfeeding
• People under 18 years of age

Necessarily talk with your doctor prior to taking Ciprofloxacin if you are suffering from epilepsy, seizures, organic lesion of the brain. If you noticed first signs of tendovaginitis(pain in the tendons), stop taking Ciprofloxacin.

Avoid direct sun rays while application of Ciprofloxacin.

Adverse effects: There are possible side-effects associated with this that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using ciprofloxacin will experience it or any other.

• Digestive system: nausea, vomiting, diarrhea, abdominal pain, pseudomembranous colitis
• CNS: dizziness, headache, tiredness, insomnia, nightmares, hallucinations, fainting, vision disorders.
• Urinary system: crystalluria, glomerulonephritis, dysuria, polyuria, proteinuria, hematuria/
• Hematopoietic system: eosinophilia, leukopenia, neutropenia, trombocytopenia
• Cardiovascular system: increased heart rate,, arrhythmia, arterial hypotension.
• reactions: skin itching, hives, Quinke's edema, arthralgia
• Other: increased photosensensitization

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with ciprofloxacin, please read the information provided with Ciprinol or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what you are already taking, including those bought without a prescription and medicines, before you start treatment with Siprobel. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.

• Didanosime lowers the absorption of ciprofloxacin
• Ciprofloxacin increases the blood levels of theophylline
• Antacids reduce the absorption of Ciprofloxacin
• Blood thinners in conjunction with Ciprofloxacin may cause bleedings
• Ciprofloxacin increases the nephrotoxic effects of cyclosporine

Additional Information: DO NOT SHARE Siprobel with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.