Duloxetine
Drug name: Duloxetine
Active Ingredients:
- duloxetine
Other names used:
- Ariclaim®
- Cymbalta®
- Xeristar®
- Yentreve®
Therapeutic actions:
Duloxetine is an antidepressant - serotonin and norepinephrine reuptake inhibitor. Duloxetine increases serotonergic and noradrenergic neurotransmission in the CNS.
Duloxetine has a central mechanism of the pain syndrome suppression, which is primarily manifested by higher threshold of pain sensitivity in the pain syndrome of neuropathic etiology.
Indications:
- Depression
- Painful form of diabetic neuropathy
Contraindications and cautions:
- Hypersensitivity
- Uncompensated angle-closure glaucoma
- Breastfeeding
- With caution: aggravation of a manic / hypomanic state, seizures, mydriasis, abnormal liver function or kidney disease, risk of suicidal attempts, pregnancy
Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Duloxetine will experience it or any other.
Often:
- dizziness (excluding vertigo)
- dry mouth, nausea, constipation
- sleep disturbance (insomnia or sleepiness), headache
Rare:
- diarrhea, vomiting, tremors, decreased appetite, weight loss
- weakness, sweating, flushing, blurred vision
- anorgasmia, decreased libido, delayed and abnormal ejaculation, erectile dysfunction
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with duloxetine, please read the information provided with Duloxetine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with duloxetine. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe. Duloxetine can interact with the following groups of drugs:
- CYP1A2 inhibitors (e.g. some antibiotics)
- antidepressants
- CYP2D6 inhibitors
- CNS depressants, including alcohol
- MAOI
- drugs with high affinity to blood proteins
Additional Information: DO NOT SHARE Duloxetine with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
Category News
H. Lundbeck A/S announces new study data published today in the journal Current Medical Research and Opinion, demonstrating that Cipralex® (escitalopram) was superior to duloxetine in the acute treatment of patients with major depressive disorder (MD
The antidepressant duloxetine hydrochloride was equally effective in reducing painful symptoms in depressed patients who did not respond, or responded only partially, to treatment with a selective s...
Data suggest that patients with generalized anxiety disorder (GAD) treated with Cymbalta(R) (duloxetine HCl) experienced improved ability to perform everyday activities at home, work and in so...
Data from a pooled analysis of three studies suggest that in patients with pain caused by diabetic nerve damage, or diabetic peripheral neuropathy, who are treated with Cymbalta (duloxetine HCl), im...
The antidepressant duloxetine, at a once-daily dose of 60 mg, significantly reduced non-specific pain and emotional symptoms associated with depression in a new, eight-week, placebo-controlled study of 327 adult patients with at least moderate pain and m
