Diflucan

Drug name: Diflucan

Other names used:

• Trican®

Active Ingredients:

• fluconazole

Therapeutic actions: Diflucan contains the active ingredient Fluconazole that belongs to a group of medications called antimycotic or antifungal. Due to inhibiting enzyme 14α- dimethylase Fluconasole disturbs the production of ergosterol that is essential component of the fungi cell, resulting in changing permeability. As a result the fungi cells become unstable and then die.

Indications: Skin infections caused by fungi such as athlete's foot (tinea pedis), ringworm (tinea corporis), jock itch (tinea cruris), pityriasis versicolor,

• Candida skin infections.
• Candida infections of the linings of the mouth (oral thrush), urinary tract, throat, lungs, bloodstream, heart, or other widespread infections of the internals.
• Vaginal thrush(vaginits) caused by Candida albicans
• Inflammation of the male genitals and/or foreskin (candidal balanitis) caused Candida albicans.
• Fungal infections caused by Cryptococcus fungi (cryptococcosis), including cryptococcal meningitis and infections affecting the lungs or skin.
• Preventing fungal infections caused by fungi in patients with a weakened immunity and low white blood cell counts due to chemotherapy, radiotherapy or bone marrow transplants.
• Prophylaxis of a disease caused by Cryptococcus fungi, eg cryptococcal meningitis, in patients with AIDS.

Contraindications and cautions: Diflucan should not be taken in allergy or hypersensitivity to Fluconazole or other anti fungal azole preparations, eg clotrimazole, ketoconazole, itraconazole and other.

D is contraindicated in pregnancy and breastfeeding. Do not use Diflucan prior to talking with your doctor if you experience the following conditions:

• Kidney and liver disorders
• Cardiovascular diseases including heart diseases(heart rate or rhythm disturbances)
• Low blood levels of calcium, magnesium or potassium.

Diflucan side effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Diflucan will experience it or any other.

Digestive system: Abdominal pain, diarrhoea, nausea and vomiting, taste changes, flatulence, dyspepsia

• CNS: headache, seizures, dizziness
• Liver disorders
• High cholesterol blood levels
• Allergic reactions: skin rash
• Decreased blood potassium levels
• Decrease in the number of white blood cells

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Diflucan, please read the information provided with Diflucan or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Diflucan. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.

Avoid concomitant use of Fluconazole and cisapride and terfenadine.

Fluconazole enhances the anti-blood-clotting effects of anticoagulants such as nicoumalone and warfarin.

Rifampicin (used for tuberculosis) reduces the blood level of fluconazole resulting in decreased therapeutic action.

Fluconazole may increase the blood levels of the following medications:

• benzodiazepines
• repaglinide
• rifabutin
• ciclosporin
• phenytoin
• sulphonylureas used to treat diabetes, eg glibenclamide, glipizide (
• tacrolimus
• theophylline
• zidovudine

Additional Information: DO NOT SHARE Diflucan with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.