Nizoral tablets

Drug name: Nizoral

Active Ingredients: ketoconazole

Therapeutic actions: Nizoral has an active ingredient ketoconazole. Nizoral is a type of drug called an antifungal. It works by interfering with yeasts and fungi cell membranes. Nizoral stops the fungi from producing a substance called ergosterol. Ergosterol is an essential component of fungal cell membranes. The decreased production of ergosterol causes holes to appear in cell membrane of fungi and this kills them .

Indications: Nizoral tablets are used to treat:

• infections of the skin, mucous membranes, mouth or throat caused by candida
• vaginal thrush (candidiasis)
• pityrosporum folliculitis
• dermatophytosis.
• vaginal yeast infections

Contraindications and cautions:
You should not use Nizoral :

• if you have liver disease.
• if you have an allergy to ketoconazole or to other antifungals.
• if you have blood disorders called porphyrias.
• If you are breastfeeding.
• If you are pregnant.
• if you are going to treat children weighing under 15kg.
• if you have rare problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.
• if you have underactivity of the adrenal glands.
• if you taking large amount of Alcohol.

Warning!

• You should tale Nizoral tablets with a meal.
• Your health care provider should monitor your liver function during the treatment with Nizoral
• You should complete you treatment till the end even if you begin to feel better.

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Nizoral will experience it or any other.

• Nausea and vomiting.
• Itching (pruritus).
• Abdominal pain.
• Diarrhoea.
• Headache.
• Dizziness.
• Sleepiness.
• Rash.

In very rare cases you can experience such side effects:

• Menstrual disorders
• Erectile dysfunction
• Serious liver disorders
• Underactivity of the adrenal glands
• Abnormal enlargement of breasts in men (gynaecomastia)
• Decreased numbers of blood cells called platelets in the blood (thrombocytopenia)
• alopecia
• Raised pressure inside the skull
• Severe swelling of lips, face or tongue (angioedema)
• Serious liver damage

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with Nozoral, please read the information provided with Nizoral or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Nizoral. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.
Especially pay attention to the following drugs:

• alprazolam (Xanax);
• anticoagulants ('blood thinners') such as warfarin (Coumadin);
• buspirone (Buspar);
• tamoxifen (Nolvadex); telithromycin (Ketek); trazodone (Desyrel); vincristine (Vincasar)
• cyclosporine (Neoral, Sandimmune);
• diazepam (Valium); digoxin (Lanoxin);
• erythromycin (E.E.S., E-Mycin, Erythrocin);
• HIV protease inhibitors such as indinavir (Crixivan), ritonavir (Norvir), and saquinavir (Invirase, Fortovase);
• medications for erectile dysfunction such as sildenafil (Viagra), tadalafil (Cialis) and vardenafil (Levitra);
• loratadine (Claritin);
• calcium channel blockers such as amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), nifedipine (Adalat, Procardia), nisoldipine (Sular),and verapamil (Calan, Covera, Isoptin, Verelan);clarithromycin (Biaxin);
• medications for diabetes;
• methadone (Dolophine); methylprednisolone (Medrol);
• midazolam (Versed); phenytoin (Dilantin); pimozide (Orap); quinidine (Quinidex, Quinaglute); quinine; tacrolimus (Prograf);

Additional Information: DO NOT SHARE Nizoral with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.