Indap

Drug name: Indap

Other names used:

• Еxtur®
• Меtindamide®
• Таndiх®
• Fludeх®
• Indaflех®
• Indapamide Аrifоn®
• Ipamix®
• Lоrvаs®
• Lozol®
• Nаtriliх®
• Servier®

Active Ingredients:

• indapamide

Therapeutic actions: Indapamide is a diuretic, which is commonly referred to as a "water pill" Specifically, it is known as an "indoline" diuretic. Indapamide is unlike any other diuretic; in fact, it is the only indoline diuretic. Although it is not entirely clear how indapamide works, it is thought that it works by increasing the amount of salt and water that the kidneys remove from the blood. This extra salt and water is passed out through urine. By increasing the amount of water removed from the blood, indapamide causes a decrease in blood volume. Because of this effect, indapamide can lower blood pressure and also help with water retention.

Indications:

• High blood pressure (hypertension) control
• Treatment of water retention (edema) due to congestive heart failure (CHF).

Contraindications and cautions: You should not take indapamide if:

• You are allergic to indapamide, or any inactive component used to make the medication. Your healthcare provider or pharmacist has a list of inactive ingredients.
• You are allergic to sulfonamides ("sulfa" drugs).
• You are not producing any urine (anuria).

You should talk with your healthcare provider prior to taking indapamide (Indap®) if you have:

• Kidney disease or kidney failure
• Diabetes
• Gout
• Fluid or electrolyte problems
• Any allergies, including allergies to sulfa drugs, foods, dyes, or preservatives.

Also, let your healthcare provider know if you:

• Are pregnant or trying to become pregnant. Indapamide is considered a pregnancy Category B medication. This means that it is probably safe to use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using indapamide during pregnancy
• Are breastfeeding

Important

• Indapamide may affect electrolytes in the blood (including sodium and potassium). Therefore, your healthcare provider will regularly check these levels. If you notice any symptoms of a possible electrolyte imbalance, contact your healthcare provider. These symptoms may include:
  • Dry mouth
  • Thirst
  • Weakness
  • Lethargy
  • Drowsiness
  • Restlessness
  • Muscle pain or muscle cramps
  • Low blood pressure (hypotension)
  • Decreased urination
  • Rapid heart rate (tachycardia) or irregular heart rhythm (arrhythmia)
  • Nausea or vomiting.

Indapamide may cause high blood sugar (hyperglycemia) in people with diabetes or (in some cases) even cause diabetes in people without a history of the condition.

Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Frequent urination may last for up to 6 hours after a dose and should decrease after you take indapamide for a few weeks. Tell your doctor if any of these symptoms are severe or do not go away:

• muscle cramps
• drowsiness
• dizziness
• confusion
• thirst
• upset stomach
• vomiting
• stomach cramps
• decreased sexual ability
• blurred vision

If you have any of the following symptoms, call your doctor immediately:

• rapid, excessive weight loss
• severe skin rash with itching
• difficulty breathing or swallowing

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

Especially pay attention to the following drugs:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen) because they may decrease Indapamide 's effectiveness
• Angiotensin-converting enzyme (ACE) inhibitors (eg, enalapril), diazoxide, or ketanserin because the risk of kidney problems may be increased
• Allopurinol, amantadine, antineoplastic agents (eg, cyclophosphamide), digitalis glycosides (eg, digoxin), lithium, or nondepolarizing muscle relaxants (eg, vecuronium) because the risk of their side effects may be increased by Indapamide

Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.