Gutron
Drug name: Gutron
Other names used:
- Amatine®
- Apo-midodrine®
- Proamatine®
Active Ingredients:
Midodrine hydrochloride
Therapeutic actions: Hypotension is low blood pressure. It is a measure of the blood pressing on the artery walls. This pressure helps move your blood around your body. You have hypotension when your blood pressure stays lower than normal. GUTRON may increase your blood pressure by constricting the walls of your blood vessels.
Indications: GUTRON is used to treat the symptoms of idiopathic orthostatic hypotension found in Bradbury-Eggleston or Shy-Drager syndromes. Idiopathic orthostatic hypotension is a fall in blood pressure that occurs upon rising abruptly to an upright position although it may also occur following a period of prolonged standing.
Contraindications and cautions: Do not take GUTRON tablets if you have had an allergy to:
- midodrine
- other alpha adrenergic receptor stimulants
- any of the ingredients listed at the end of this leaflet
Do not take GUTRON tablets if you have any of the following medical conditions:
- heart disease
- kidney failure
- urinary retention
- pheochromocytoma - a tumor of the adrenal glands
- thyrotoxicosis - a condition resulting from an overactive thyroid gland
- tachyarrhythmias or ventricular fibrillation - an abnormal heartbeat
Do not take GUTRON tablets if you are under the age of 12 years.
There is inadequate information about the use of GUTRON in children.
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Gutron May cause an allergic reaction. Symptoms of an allergic reaction to GUTRON tablets may include:
- asthma, shortness of breath, wheezing
- swelling of the face, lips, or tongue which may lead to difficulty swallowing or breathing
- rash, itching or hives
- fainting
The most serious and frequent adverse reaction to midodrine is supine hypertension. The other frequent adverse reaction to midodrine is pruritus.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
- Cardiac glycosides such as digitalis and digoxin. These are medicines taken for heart conditions and are used to reduce heart rate. They may enhance or cause bradycardia, abnormal heart beat or may stop the small electrical impulse that travels through the heart.
- Vasoconstrictor sympathomimetic medicines such as phenylephrine, methoxamine and dihydroergotamine. They may enhance the effects of GUTRON.
- Salt retaining steroids such as fludrocortisone. You may experience supine hypertension which may be minimised by either reducing the dose of fludrocortisone or decreasing salt intake prior to starting treatment with GUTRON tablets.
- Alpha adrenergic blocking agents - GUTRON is an alpha adrenergic receptor stimulant and blocking agents cancel the action of GUTRON.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
