Lopril

Drug name: Lopril

Other names used:

• Zestril®

Active Ingredients: Lisinopril

Therapeutic actions: Lisinopril is in a group of drugs called ACE inhibitors. ACE stands for angiotensin converting enzyme. It works by decreasing certain chemicals that tighten the blood vessels, so blood flows more smoothly and the heart can pump blood more efficiently.

Indications: Lisinopril is used to treat high blood pressure (hypertension), congestive heart failure, and to improve survival after a heart attack. Lisinopril comes as a tablet to take by mouth. It is usually taken once a day. Your doctor will probably start you on a low dose of lisinopril and gradually increase your dose.

Contraindications and cautions: Do not use this medication if you are allergic to lisinopril or to any other ACE inhibitor, such as benazopril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik).

Before using lisinopril, tell your doctor if you are allergic to any drugs, or if you have:

• kidney disease (or if you are on dialysis);
• liver disease;
• heart disease or congestive heart failure;
• diabetes; or
• a connective tissue disease such as Marfan syndrome, Sjogren's syndrome, lupus, scleroderma, or rheumatoid arthritis.

If you have any of these conditions, you may not be able to use lisinopril, or you may need a dosage adjustment or special tests during treatment.

FDA pregnancy category D. Do not use this medication without telling your doctor if you are pregnant or planning a pregnancy. Lisinopril could cause birth defects in the baby if you take the medication during pregnancy. Use an effective form of birth control. Stop using this medication and tell your doctor right away if you become pregnant during treatment. It is not known whether lisinopril passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Lisinopril may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• cough
• dizziness
• headache
• excessive tiredness
• upset stomach
• diarrhea
• weakness
• sneezing
• runny nose
• decrease in sexual ability
• rash

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• hoarseness
• difficulty breathing or swallowing
• fever, sore throat, chills, and other signs of infection
• yellowing of the skin or eyes
• lightheadedness
• fainting
• chest pain

Lisinopril may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

Interactions: Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.

Before taking lisinopril, tell your doctor if you are taking any of the following drugs:

• lithium (Lithobid, Eskalith);
• a potassium supplement such as K-Dur, Klor-Con;
• salt substitutes that contain potassium;
• insulin or Diabetes medication you take by mouth;
• aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis), ketorolac (Toradol), mefenamic acid (Ponstel), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn), piroxicam (Feldene); or
• a Diuretic (water pill) such as amiloride (Midamor), bumetanide (Bumex), chlorthalidone (Hygroton, Thalitone), ethacrynic acid (Edecrin), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril), indapamide (Lozol), metolazone (Mykrox, Zarxolyn), spironolactone (Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex).

If you are using any of these drugs, you may not be able to use lisinopril or you may need dosage adjustments or special tests during treatment.

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Drug name: Lopril H
Brand name: Zestoretic, Prinzide
Active Ingredients: Lisinopril, Hydrochlorothiazide

Therapeutic actions: Lopril H is used in the treatment of high blood pressure. It combines an ACE inhibitor drug with a diuretic. Lisinopril, the ACE inhibitor, works by limiting production of a substance that promotes salt and water retention in your body. Hydrochlorothiazide, a diuretic, prompts your body to produce and eliminate more urine, which helps in lowering blood pressure. Combination products such as Lopril H are usually not prescribed until therapy is already under way.

Indications: You must take Lopril H regularly for it to be effective. Since blood pressure declines gradually, it may be several weeks before you get the full benefit of Lopril H; and you must continue taking it even if you are feeling well. Lopril H does not cure high blood pressure; it merely keeps it under control.

Contraindications and cautions: if you develop swelling of your face, lips, tongue, or throat, or of your arms and legs, or have difficulty swallowing or breathing, you should stop taking the drug and contact your doctor immediately. You may need emergency treatment.

Lopril H may cause your blood pressure to become too low. If you feel light-headed, especially during the first few days of treatment, inform your doctor. If you actually faint, stop taking Lopril H until you have consulted your doctor.

Do not use salt substitutes containing potassium without first consulting your doctor.

Excessive sweating, dehydration, severe diarrhea, or vomiting could cause you to lose too much water and cause your blood pressure to drop dangerously.

If you develop chest pain, a sore throat, or fever and chills, contact your doctor immediately. It could indicate a more serious illness.

Make sure the doctor knows if you have congestive heart failure or other heart problems, diabetes, liver disease, a history of allergy or bronchial asthma, or lupus erythematosus (an arthritis-like disease sometimes accompanied by rashes). Lopril H should be used cautiously. If you have kidney disease, your doctor should monitor your kidney function regularly.

If you are undergoing desensitization to bee or wasp venom, Lopril H may cause a severe allergic reaction.

This medication is not recommended for people on dialysis; severe allergic reactions have occurred.

If you notice a yellowish cast to your skin or eyes, stop taking Lopril H and contact your doctor immediately.

If you are diabetic, your doctor will want to keep an eye on your blood sugar levels.

Before any surgery, make sure your doctor or dentist knows you are taking Lopril H.

Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Prinzide.

• More common side effects may include:
  Cough, dizziness, dizziness when standing up, fatigue, headache

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

Interactions: Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.

Prinzide may intensify the effects of alcohol. Do not drink alcohol while taking Prinzide.

If Prinzide is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Prinzide with the following:

Barbiturates such as Nembutal and Seconal

Cholestyramine (Questran)

Colestipol (Colestid)

Corticosteroids such as prednisone

High blood pressure drugs such as Procardia XL and Aldomet

Indomethacin (Indocin)

Insulin

Lithium (Lithonate)

Narcotics such as Darvon and Dilaudid

Nonsteroidal anti-inflammatory drugs such as Naprosyn

Oral antidiabetic drugs such as Micronase

Potassium supplements such as K-Dur and Slow-K

Potassium-containing salt substitutes

Potassium-sparing diuretics such as Midamor

Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.