Dolac
Drug name: Dolac
Other names used:
- Ketorolac®
Active Ingredients:
Ketorolac
Therapeutic actions: Ketorolac is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ketorolac works by reducing hormones that cause inflammation and pain in the body.
Indications: Dolac is a prescription medication that has been licensed for the short-term relief of moderate to severe pain. Short-term is defined as no more than five days. Dolac is most often used for pain relief following a procedure but may also be used for such things as back pain, cancer pain, or pain caused by kidney stones.
Contraindications and cautions:
You should not take Dolac if you:
- Are allergic to Dolac, (ketorolac), or any inactive components used in making Dolac. Your healthcare provider or pharmacist has a list of the inactive ingredients.
- Have an active bleeding condition -- such as a stomach ulcer or bleeding within the head -- or are at high risk of bleeding.
- Have a history of gastrointestinal bleeding or GI perforation (which is a hole in the digestive system).
- Have severe kidney disease or kidney failure.
- Have an allergic reaction, hives, or asthma caused by aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).
- Are having or have recently had coronary bypass graft surgery (often known as open heart surgery, bypass surgery, or just CABG).
- Are currently taking aspirin or other NSAIDs.
- Are taking probenecid (Benemid®, Probalan®).
- Are in the third trimester of pregnancy, in labor, or nursing.
Before taking Dolac (ketorolac) let your healthcare provider know if you have:
- Asthma
- Heart disease, including congestive heart failure
- High blood pressure (hypertension)
- Liver disease or liver failure
- Kidney disease or kidney failure
- Bleeding problems (or if you are taking medicine that decreases your blood's ability to clot)
- Diabetes
- Nasal polyps
- Seizures
- A history of hallucinations
- Systemic lupus erythematosus (lupus or SLE)
- Stomach ulcers, stomach bleeding, or a history of either condition
- Any allergies to medicines, including aspirin or other NSAID pain medicines.
Also, let your healthcare provider know if you:
- Are pregnant or are thinking about becoming pregnant
- Are breastfeeding
- Drink alcohol frequently
- Smoke
- Are having or have recently had heart surgery.
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Ketorolac may cause side effects.
- headache
- dizziness
- drowsiness
- diarrhea
- constipation
- gas
- sores in the mouth
- sweating
Some side effects can be serious.
- fever
- blisters
- yellowing of the skin or eyes
- excessive tiredness
- unusual bleeding or bruising
- lack of energy
- upset stomach
- loss of appetite
- pain in the upper right part of the stomach
- flu-like symptoms
- pale skin
- fast hearbeat
- cloudy, discolored, or bloody urine
- back pain
- difficult or painful urination
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
Especially pay attention to the following drugs:
- Aspirin
- Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Motrin®, Advil®), naproxen (Naprosyn®), naproxen sodium (Aleve®, Anaprox®, Naprelan®), diclofenac (Cataflam®, Voltaren®), indomethacin (Indocin®), nabumetone (Relafen®), oxaprozin (Daypro®), celecoxib (Celebrex®), meloxicam (Mobic®), etodolac (Lodine®), ketoprofen, and others
- Warfarin (Coumadin®, Jantoven®) or heparin
- Probenecid (Benemid®, Probalan®)
- Angiotensin-converting enzyme inhibitors (ACE inhibitors), such as lisinopril (Zestril®, Prinivil®), fosinopril (Monopril®), captopril (Capoten®), quinapril (Accupril®), benazepril (Lotensin®), enalapril (Vasotec®), and ramipril (Altace®)
- Diuretics, such as torsemide (Demadex®), furosemide (Lasix®), and hydrochlorothiazide
- Lithium (Eskalith®, Lithane®, Lithonate®, Lithotabs®)
- Methotrexate (Rheumatrex®, Trexall™)
- Muscle relaxants
- Seizure medicines, such as phenytoin (Dilantin®, Phenytek®) and carbamazepine (Carbatrol®, Epitol®, Tegretol®, Tegretol®-XR, Equetro™)
- Psychoactive drugs, such as fluoxetine (Prozac®), thiothixene (Navane®), and alprazolam (Xanax®, Xanax XR®, Niravam™).
Several herbal and nutritional supplements can also interact with Toradol and may increase the risk of bleeding. Examples of these include (but are not limited to):
- Dong quai
- Feverfew
- Garlic
- Ginger
- Ginkgo biloba
- Ginseng
- St. John's wort
- Fish oil supplements.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.

