Ketanov
Drug name: Ketanov
Other names used:
- Toradol®
Active Ingredients:
Ketorolac
Therapeutic actions: Ketanov works by stopping the body's production of a substance that causes pain, fever, and inflammation. The primary mechanism of action responsible for Ketorolac's anti-inflammatory/antipyretic/analgesic effects is the inhibition of prostaglandin synthesis by competitive blocking of the the enzyme cyclooxygenase (COX). Like most NSAIDs, Ketorolac is a non-selective cyclooxygenase inhibitor.
As with other NSAIDs, the mechanism of the drug is associated with the chiral S form. Conversion of the R enantiomer into the S enantiomer has been shown to occur in the metabolism of ibuprofen; it is unknown whether it occurs in the metabolism of ketorolac.
Indications: Ketorolac is used to relieve moderately severe pain, usually after surgery. Ketorolac is in a class of medications called NSAIDs. Ketorolac comes as a tablet to take by mouth. It is usually taken every 4-6 hours on a schedule or as needed for pain. If you are taking ketorolac on a schedule, take it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Contraindications and cautions:
Before taking ketorolac,
- do not take ketorolac if you are taking probenecid.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: antidepressants; medications for anxietyor mental illness; medications for seizures such as phenytoin (Dilantin) or carbamazepine (Tegretol); methotrexate (Rheumatrex); sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
- tell your doctor if you have or have ever had the conditions mentioned in the IMPORTANT WARNING section or swelling of the hands, feet, ankles, or lower legs.
- tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, or you plan to become pregnant. If you become pregnant while taking ketorolac, call your doctor.
- you should know that this medication may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how this medication affects you.
- remember that alcohol can add to the drowsiness caused by this medication. Talk to your doctor about the safe use of alcohol while taking this medication.
Use with Care in:
- Pregnancy and breast feeding
- Children under 16 years
- Blood clotting disorders
- Peptic ulcers
Not to be used in:
- Liver and kidney disorders
- Gastro-intestinal disease
- Elderly
- Asthma
Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
Ketorolac may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- Dizziness
- Drowsiness
- Diarrhea
- Constipation
- Gas
- sores in the mouth
- sweating
Some side effects can be serious. If you experience any of the following symptoms, or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more ketorolac until you speak to your doctor.
- fever
- blisters
- yellowing of the skin or eyes
- excessive tiredness
- unusual bleeding or bruising
- lack of energy
- upset stomach
- loss of appetite
- pain in the upper right part of the stomach
- flu-like symptoms
- pale skin
- fast hearbeat
- cloudy, discolored, or bloody urine
- back pain
- difficult or painful urination
Ketorolac may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
Interactions: Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.
Ketanov interacts with such drugs as: Warfarin, Digoxin, Salicylate, and Heparin, Aspirin, Diuretics, Probenecid, Lithium, Methotrexate, ACE Inhibitors, Antiepileptic Drugs, Psychoactive Drugs, Pentoxifylline, Nondepolarizing Muscle Relaxants.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
