De-nol
Drug name: De-nol
Other names used:
- CBS®
- Colloidal Bismuth Subcitrate®
- Tripotassium Dicitratobismuthate®
Active Ingredients:
bismuth, tripotassium dicitrato
Therapeutic actions: Bismuth has several actions in the gut. It forms a coating over ulcers in the stomach and gut protecting them from stomach acid and allowing them to heal. It also kills bacteria , including those which are now believed to aggravate ulcers. De-nol increases the synthesis of prostoglandin E, enhances the secretion of bicarbonate, stimulates the activity of the cells protective mechanisms. It increases the stability of mucous membrane in digestive system to the action of pepsin, hydrochloric acid, ferments and salts of the bilious acids. The activity of pepsin and pepsinogen is also decreased.
Indications: De-nol is used to treat:
- Duodenal ulcers
- Gastric ulcers (stomach ulcers)
- Diarrhea
- Nausea
- Upset stomach characterized by stomach pain and burning, nausea and excess gas (dyspepsia)
Contraindications and cautions:
You should not use De-nol:
- If you have an allergy to any of Bismuth salts
- If you have any kidney disease
- Avoid use of aspirin and other salicylates
You should talk with your health care provider prior to taking De-nol if you:
- Are pregnant or plan to become pregnant while using this medicine
- Are breastfeeding
- Have any other health problems, such as diabetes, gout, high blood pressure, liver or kidney problems, or heart or blood vessel disease
- This medicine may discolor the stools, but this is harmless.
Warning!
- You should not use this medication more than 8 weeks.
- During the treatment you should not use other medications, containing Bismuth
- Large doses may lead to confusion, changes in memory and mood, hallucinations, seizures
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
- Nausea and vomiting
- Skin rashes
- Brain disorders (encephalopathy)
- Irritation to the lining or movements of the gut
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
These interactions include:
- Antacids : Tums (R), cimetidine Tagamet(R), famotidine Pepcid(R), ranitidine Zantac(R)
- Bismuth Subcitrate should not be taken with milk or food. Take it 30 minutes before or 2 hours after meals
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
