Fragmin

Drug name: Fragmin

Therapeutic actions: Dalteparin is an anticoagulant (blood thinner). Dalteparin prevents the formation of blood clots.

Indications: Fragmin is primarily used in preventing the formation of blood clots in patients who will undergo hip replacement surgery or abdominal surgery. Fragmin is also used in treating certain types of angina and heart attacks. Fragmin is also used in preventing complications of blood clots in patients who are taking aspirin. Fragmin may also be used for purposes other than those indicated here.

Contraindications and cautions: Do not use dalteparin without first talking to your doctor if you

have a very low level of platelets in your blood,
have uncontrolled active bleeding,
have an to pork products, or
cannot have accurate blood testing done prior to and during dosing.

Before using dalteparin, tell your doctor if you

have bacterial endocarditis,
have high blood pressure that is not being controlled,
need to have surgery or another invasive procedure,
have hemophilia or another blood disorder,
have a stomach ulcer,
have due to or high blood pressure,
have liver disease, or
have kidney disease.

You may not be able to use dalteparin, or you may require a dosage adjustment or special monitoring during therapy if you have any of the conditions listed above.
Dalteparin (Normiflo) is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not use dalteparin without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether dalteparin passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.
Do not take aspirin, ibuprofen (Motrin, Advil, Nuprin, and others), ketoprofen (Orudis KT, Orudis, Oruvail), naproxen (Aleve, Naprosyn, Anaprox, and others), indomethacin (Indocin), or any other nonsteroidal medication without first talking to your doctor. These may lead to bleeding when taken with dalteparin. Ask your pharmacist or doctor before taking any prescription or over-the-counter medications, including vitamins, minerals, and products.

Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this will experience that or any side effect.
Fragmin may have any of the following serious side effects and reactions:

Difficulty in breathing
Closing of the throat
Swelling of the lips, tongue or face
Hives
Any prolonged or unexplained bleeding
Pain, warmth, or redness in an arm or leg
Ulceration at the injection site

If you experience any of these, discontinue use of Fragmin and inform your doctor.
Fragmin may also have less serious side effects that are more likely to occur. They include the following:

Mild pain, redness or warmth at injection site
Rash or itching
Fever

If you experience any of these, continue using the product but inform your doctor immediately. Other side effects may also occur when you take Fragmin. Inform your doctor if you experience anything unusual while or after taking Fragmin.

Interactions: There is a risk of bleeding in the spinal or epidural space, possibly resulting in paralysis, when dalteparin is used along with spinal or epidural anesthesia or spinal puncture. This risk may be increased by the use of indwelling epidural catheters or by the concomitant use of that affect blood clotting.
Do not take dalteparin with any of the following medicines without first talking to your doctor:

aspirin,
ibuprofen (Motrin, Advil, Nuprin, and others), ketoprofen (Orudis KT, Orudis, Oruvail), naproxen (Aleve, Naprosyn, Anaprox, and others), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ketorolac (Toradol), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), or any other nonsteroidal anti-inflammatory medication;
warfarin (Coumadin);
aspirin and dipyridamole (Aggrenox);
ticlopidine (Ticlid) or clopidogrel (Plavix); or
dipyridamole (Persantine).

The listed above may increase the effects of dalteparin, which could be dangerous. You may not be able to take dalteparin, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
Drugs other than those listed here may also interact with dalteparin. Talk to your doctor and pharmacist before using any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.